Three F-16 fighter jets bombed three ISIL targets from Diyarbakir airbase shortly before 4am local time on Friday, Turkish Prime Minister Ahmet Davutoglu's office said in a statement.
"Four guided bombs targeted two headquarters and an assembly point," the statement said.
Meanwhile, Turkish anti-terrorism police raided more than 100 suspected ISIL, Kurdish and leftist armed group locations in Istanbul in an overnight operation on Friday.
The number of detained was not immediately clear.
One member of the Marxist Revolutionary People's Liberation Party Front (DHKP/C), was killed in an exchange of fire with police forces during the raids in the Bagcilar neighbourhood of Istanbul.
The raids, carried out in 26 districts of the city, were supported by 5,000 police officers and helicopters.
The police conducted a separate set of raids in the Turkish capital, Ankara. At least nine people were detained in 12 different locations.
In total, similar operations were carried out in 13 provinces of Turkey that resulted in 251 detentions, according to the coordination centre of the Turkish Prime Ministry.